Comfortis PLUS for Dogs 27-54 kg - Brown 6 Pack

Comfortis Plus (previously labelled Panoramis) kills fleas FAST* PLUS protects against intestinal worms and deadly heartworm

• Starts killing fleas in just 30 minutes
• Prevents potentially fatal heartworm disease
• Protects against intestinal parasites
• Available in a convenient beef flavoured chewable tablet
• Safe for puppies from 8 weeks of age

This is an Australian labelled pack (made in the United States) and due to a manufacturer restriction can't be shipped to the United States

Comfortis Plus starts killing fleas in just 30 minutes, plus provides the added benefit of protection against deadly heartworm and intestinal worms. For immediate relief and month long protection Comfortis Plus is available in a convenient beef flavoured, chewable tablet.

Unlike spot on treatments there is no harmful reside that can rub or wash off, making Comfortis Plus the perfect choice for pet owners with young children or for dogs that are bathed regularly or enjoy a swim. Comfortis Plus is an ideal choice for:

• Dog owners who dislike mess and inconvenience
• Households with children or other pets
• Dogs that swim or are washed frequently
• Dogs with dermatological (skin) conditions requiring topical therapy

Important Safety Information

Comfortis Plus can be administered to puppies from 8 weeks of age. Puppies less than 14 weeks of age may experience an increased rate of vomiting. Seek veterinary advice regarding the use of Comfortis Plus in pregnant and lactating females, and in dogs with pre-existing epilepsy.

The safe use of Comfortis Plus in breeding males has not been evaluated.

Concurrent use of Comfortis Plus with high extra-label doses of ivermectin for parasitic mange or demodicosis may be associated with an increased risk of developing neurological signs typically associated with ivermectin toxicity. Comfortis Plus should not be administered concurrently with extra-label high doses of macrocyclic lactones.

The use of Comfortis Plus in dogs suffering from microfilaremia is not recommended. On rare occasions, transient shock-like (hypersensitivity) reactions have been observed in heartworm positive animals carrying a high number of microfilariae at the time of the first treatment with milbemycin oxime. Dogs with an existing adult immitis heartworm infection should be treated with an adulticide prior to commencement of Comfortis Plus.

The following adverse events have been recorded following administration of spinosad and milbemycin oxime together: vomiting, pruritis, lethargy and diarrhoea.

Active Ingredients

Comfortis Plus Chewable Tablets are available in variable strengths of spinosad + milbemycin oxime for oral administration to dogs.

Milbemycin oxime interferes with nerve transmission in invertebrates, which helps protect against heartworm, roundworm, hookworm and whipworm (minimum dose rate 0.5mg/kg).

Comfortis Plus (spinosad + milbemycin oxime) Chewable Tablets are flavoured tablets and each tablet contains:

140 mg spinosad and 2.3 mg milbemycin oxime for dogs 2.3 - 4.5 kg

270 mg spinosad and 4.5 mg milbemycin oxime for dogs 4.6 - 9 kg

560 mg spinosad and 9.3 mg milbemycin oxime for dogs 9.1 - 18 kg

810 mg spinosad and 13.5 mg milbemycin oxime for dogs 18.1 - 27 kg

1620 mg spinosad and 27 mg milbemycin oxime for dogs 27.1 - 54 kg.

Directions For Use

Comfortis Plus should be administered with food for maximum effectiveness. Comfortis Plus may be consumed as a treat by dogs when offered by the owner just prior to feeding. AlternativelyComfortis Plusmay be offered in food or administered like other tablet medications, in conjunction with a meal. To ensure that the entire dose is consumed, watch your dog for several minutes following tablet administration. If the entire dose is not consumed, re-dose as soon as possible with the full dose.

Comfortis Plustablets are given orally, once a month at the recommended minimum dosage of 30 mg/kg body weight spinosad and 0.5 mg/kg milbemycin oxime as specified in the following table

* Spinosad starts to kill fleas in 30 minutes and is 100% effective in dogs within 4 hours - Elanco study T9C060330, data on file.1